Research

And Grants

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Home > Research and Grants

The Cure Starts Now has funded $26,366,182 (USD) in pediatric brain cancer research in partnership with the DIPG / DMG Collaborative. This includes 175 grants at over 100 hospitals in 29 countries.




The Hospital for Sick Children - $194,260

Amount
$194,260.00
Date
September 2016

Exploring the interactome of H3K27M to find therapeutic targets for DIPG

Grant Information

Cold Spring Harbor Laboratory - $100,000

Amount
$100,000.00
Date
September 2016

Allele-specific antisense therapy for DIPG

Grant Information

Children's Cancer Institute - $143,884

Amount
$143,884.00
Date
September 2016

Radiosensitisation of Diffuse Intrinsic Pontine Gliomas by modulating the glucose metabolism

Grant Information

Dana-Farber Cancer Institute - $100,000

Amount
$100,000.00
Date
December 2015

Characterizing resistance mechanisms to radiation therapy and adjuvant chemotherapy in Diffuse Intrinsic Pontine Glioma

Grant Information

Cincinnati Children's Hospital Medical Center - $100,000

Amount
$100,000.00
Date
December 2015

An early Phase 2 Study of LEE011, a CDK4/6 Inhibitor, following radiation therapy in Children with Newly Diagnosed non-biopsied Diffuse Pontine Gliomas (DIPG) and Rb+ biopsied DIPG and High Grade Gliomas (HGG)

Grant Information

Baylor College of Medicine/Texas Children's Hospital - $200,000

Amount
$200,000.00
Date
December 2015

Targeting DIPGs through Super-activation of Steroid Receptor Co-activators: An in vivo Study in Patient-derived Intra-brain Stem Xenograft Mouse Models

Grant Information

Children's National Health System and Children's Research Institute - $125,000

Amount
$125,000.00
Date
December 2015

Comprehensive Molecular-Based Cross-Species Comparison of DIPG Biology

Grant Information

Boston Children's Hospital - $110,000

Amount
$110,000.00
Date
December 2015

Enabling epigenetic therapies by exploring DIPG chromatin sensitivities

Grant Information

UCL Institute of Child Health - $200,000

Amount
$200,000.00
Date
December 2015

T-cell based immunotherapy for DIPG.

Grant Information

Dana Farber Cancer Institute - $82,863

Amount
$82,863.00
Date
December 2015

Discovering novel epigenetic dependencies in Diffuse Intrinsic Pontine Glioma

Grant Information

VU University Medical Center - $92,950

Amount
$92,950.00
Date
November 2015

Liquid Biopsies for the Monitoring of Diffuse Intrinsic Pontine Glioma.

Grant Information

Children's Cancer Institute - $145,341

Amount
$145,341.00
Date
November 2015

Fenretinide, a novel agent targeting RTK/PI3K/AKT network for the treatment of Diffuse Intrinsic Pontine Glioma.

Grant Information

Cincinnati Children's Hospital Medical Center - $200,000

Amount
$200,000.00
Date
October 2015

Intra-tumoral heterogeneity in diffuse intrinsic pontine and midline high-grade gliomas

Grant Information

The Hospital for Sick Children - $190,905

Amount
$190,905.00
Date
October 2015

Mitochondrial DNA alterations and their potential as a novel therapeutic target in DIPG

Grant Information

Children's National Medical Center - $200,000

Amount
$200,000.00
Date
October 2015

Evaluating TORC1/2 kinase inhibition in murine and nonhuman primate (NHP) models

Grant Information